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Writer's pictureMohammed A Rashad

Supply Shortage Alert: Novo Nordisk's Ozempic and Victoza in High Demand

Updated: Aug 21


Why are thousands of diabetes patients in the UK suddenly scrambling to find their medications? The recent announcement from Novo Nordisk about the supply shortages of Ozempic and Victoza has sent ripples through the healthcare community. These GLP-1 receptor agonists, crucial for managing type 2 diabetes, are now in high demand, leaving many to wonder how they will maintain their treatment regimens amidst the scarcity.


This shortage isn't just a minor inconvenience; it's a significant challenge that could impact the health and well-being of countless individuals. With Ozempic facing intermittent supply issues and Victoza expected to be out of stock until the end of 2024, both patients and healthcare providers are navigating uncharted waters. As the demand continues to outpace supply, understanding the implications and exploring alternative solutions becomes more critical than ever. 


Read our blog to uncover the full story and learn how to manage this pressing issue effectively.


Key Takeaways


What Are GLP-1 RAs?


Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are a class of medications used primarily to manage type 2 diabetes. They work by mimicking the action of the GLP-1 hormone, which helps regulate blood sugar levels by enhancing insulin secretion, slowing gastric emptying, and reducing appetite. 


This makes them effective for blood sugar control and weight management, a significant benefit for many patients.


The Role of Ozempic and Victoza

Ozempic (semaglutide) and Victoza (liraglutide) are two of the most popular GLP-1 RAs in the UK. Manufactured by Novo Nordisk, these medications have gained a reputation for their efficacy in controlling blood glucose levels and promoting weight loss. Ozempic, in particular, has been noted for its once-weekly dosing, which offers patients convenience. 


However, with the current supply shortage, patients and healthcare providers face new challenges in maintaining effective diabetes management.


Details of the Current Shortage


Intermittent Supply and Out-of-Stock Issues

Novo Nordisk has announced that Ozempic will experience intermittent supply issues, while Victoza is expected to be out of stock until the end of 2024. This shortage is not due to safety or quality concerns but rather a significant increase in demand. 


As more patients seek the benefits of these medications, the supply chain has struggled to keep pace.


Impact on Patients and Healthcare Providers

The shortage has created a ripple effect across the healthcare system. Patients who rely on these medications for their diabetes management are now faced with uncertainty. 


Healthcare providers must navigate these challenges by finding alternative treatments and ensuring that patients continue to receive the care they need.


 

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National Patient Safety Alert


Key Recommendations

In response to the shortage, the Department of Health and Social Care (DHSC) has issued a National Patient Safety Alert (NatPSA/2024/001/DHSC). This alert provides crucial guidance for healthcare providers, including:


  • Notifying Patients: Inform patients about the shortage and discuss potential impacts on their treatment plans.

  • Alternative Treatments: Consider alternative medications, such as Rybelsus tablets, which contain the same active ingredient as Ozempic.

  • Clinical Supervision: Ensure that any changes in medication are closely monitored to maintain patient safety and efficacy.


Prescription Guidelines

The alert also emphasises the importance of prescribing GLP-1 RAs for licensed indications only. This means prioritising stock for patients with type 2 diabetes and avoiding off-label use, which could exacerbate the shortage.


Exploring Alternative Treatment Options


Rybelsus Tablets

Rybelsus, an oral form of semaglutide, offers a viable alternative for patients affected by the Ozempic shortage. While it requires daily dosing, it provides similar benefits in terms of blood sugar control and weight management. 


Healthcare providers should consider this option for patients who may benefit from a switch.

Other GLP-1 RAs

Depending on patient needs and availability, other GLP-1 RAs may be considered in addition to Rybelsus. Healthcare providers must evaluate each patient's situation individually and make informed decisions about alternative treatments.


Strategies for Safe Medication Switches

Switching medications can be challenging, but with careful planning and supervision, risks can be minimised. Healthcare providers should:


  • Assess Patient Needs: Evaluate the patient's current health status and treatment goals.

  • Monitor Closely: Implement regular follow-ups to monitor the patient's response to the new medication.

  • Educate Patients: Provide clear instructions and information about potential side effects and what to expect during the transition.


Reporting Adverse Reactions

Healthcare professionals are encouraged to report any suspected adverse drug reactions via the Yellow Card scheme. This helps gather data on the safety and efficacy of alternative treatments and ensures that any issues are addressed promptly.


Impact on Patients


Managing Diabetes Amidst Shortages

For patients, the shortage of Ozempic and Victoza can be a source of stress and concern. Patients must stay informed and proactive in managing their condition. Here are some tips:


  • Communicate with Healthcare Providers: Keep an open line of communication with your healthcare team to discuss any concerns or changes in your treatment plan.

  • Stay Informed: Keep up-to-date with the latest information on the shortage and any new developments.

  • Adhere to Treatment Plans: Follow your healthcare provider's instructions carefully to ensure the best possible outcomes.


Addressing Common Concerns

Patients may have questions about the effects of switching medications, such as potential side effects or changes in efficacy. It is important to address these concerns with your healthcare provider and seek support if needed.


Conclusion

The supply shortage of Ozempic and Victoza presents a significant challenge for both patients and healthcare providers in the UK. By understanding the situation, exploring alternative treatments, and prioritising patient safety, we can navigate this complex issue effectively. Staying informed and proactive is key to ensuring that diabetes management remains effective and that patients continue to receive the care they need.


Struggling with medication management amidst the current shortages? The Medicines Management Team is here to support your practice or PCN. Our experienced leadership, comprising advanced clinical practitioners and GPs, is dedicated to delivering efficient medicines management services.


Reach out to us today to learn how we can assist you.


FAQs

Is Ozempic used for weight loss?

Yes, Ozempic is primarily prescribed for managing type 2 diabetes, but it also has the added benefit of aiding weight loss. It works by reducing appetite and slowing digestion, which can help patients lose weight as part of a comprehensive treatment plan.

Can you get Ozempic in the UK for weight loss?

Is Ozempic available on the NHS?

How much weight do you lose in a month with Ozempic?


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