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Writer's pictureMohammed A Rashad

Cyclizine for Motion Sickness: Your Ultimate Guide

Updated: Aug 27

Cyclizine for Motion Sickness by TMMT

Imagine planning a road trip with friends, but your fear of motion sickness is holding you back. A Cyclizine 100mg or 50 mg dosage might be the solution you need. This comprehensive guide explores how Cyclizine works, its benefits, and the best practices for effective use.


Whether you're a clinical pharmacist or simply managing your medicine, understanding Cyclizine is crucial for a smoother, more comfortable journey.


Key Takeaways


What is Cyclizine?


Cyclizine is an antiemetic drug famous for preventing nausea, vomiting, and dizziness caused by motion sickness while travelling. It belongs to a class of medications known as antihistamines, specifically the piperazine derivatives.


Cyclizine is available in various forms, including tablets, chewable tablets, and injections, making it a versatile option for different patient needs. Its efficacy and relatively low side effect profile have made it popular among healthcare providers and patients.


It can also be used to manage postoperative nausea and vomiting, as well as nausea related to pregnancy and other medical conditions.


 

Enhance your clinical services with our Clinical Pharmacists for your PCN, GP Practice, or Federation.


 

Origin of Cyclizine


Cyclizine was first synthesized in the mid-20th century as part of efforts to develop effective treatments for motion sickness and related conditions. Its development was driven by the need for a reliable antiemetic that could be easily administered and tolerated by a wide range of patients.


Since its introduction, Cyclizine has been extensively studied and used in clinical practice, establishing its place in medicine management.


Over the years, Cyclizine has been included in various clinical guidelines and has become a staple in over-the-counter and prescription medicine management for motion sickness.


Clinical pharmacists often recommend Cyclizine due to its proven track record and effectiveness, making it an essential medication for managing nausea and vomiting.


How Cyclizine Works

Cyclizine for Motion Sickness by TMMT

Cyclizine's primary function is to block H1 histamine receptors and muscarinic receptors in the brain. This dual action interferes with the activity of histamine and acetylcholine, neurotransmitters that play a key role in triggering nausea and vomiting.


Cyclizine stabilizes the vestibular system in the inner ear by inhibiting receptors responsible for balance and spatial orientation. This stabilization helps prevent the brain from receiving mixed signals that cause motion sickness, effectively reducing symptoms such as nausea, dizziness, and vomiting during travel.


Uses and Benefits of Cyclizine


Cyclizine is a versatile medication with several important uses and benefits, making it a valuable addition to your medicine cabinet.


Benefits

  • Efficacy in preventing nausea and vomiting: Cyclizine has a proven track record of reducing symptoms quickly and effectively, relieving many users.

  • Convenience of use: Cyclizine is available in various forms, such as tablets and injections, and is easy to administer and incorporate into your routine.


Dosage and Administration


Understanding the correct Cyclizine dosage and how to take Cyclizine is crucial for its effectiveness and safety.


Standard dosages for adults and children: The typical dosage for adults and children over 12 years old is 50 mg- 100 mg taken up to three times a day. For children aged 6-12, the recommended Cylizine dosage is 25 mg taken up to three times a day.


Special considerations for different age groups and conditions: The dosage may need to be adjusted for elderly patients or those with specific medical conditions. Always follow the prescribing guidelines provided by your healthcare provider or pharmacist.


 

Enhance your clinical services with our Clinical Pharmacists for your PCN, GP Practice, or Federation.


 

How to Take Cyclizine

Cyclizine for Motion Sickness by TMMT

For NHS patient access and comprehensive pharmacy services, always consult your healthcare provider to ensure Cyclizine is the right solution for your needs.

Effective patient access in the UK often involves discussing options with your clinical pharmacist to tailor the best treatment plan.

  • Methods of administration: Cyclizine can be taken as tablets, chewable tablets, or via injection. Tablets should be swallowed whole with water, while injections should be administered by a healthcare professional or clinical pharmacist.

  • Timing and frequency of doses: For optimal effectiveness, take Cyclizine 30 minutes before travel or as prescribed by your pharmacist. The dosing frequency typically ranges from 1-3 times daily, depending on the condition being treated.


Use During Pregnancy and Breastfeeding

  • Safety considerations: Cyclizine in pregnancy is often used to manage nausea and vomiting, known as morning sickness. However, it should only be used under the guidance of a healthcare provider.

  • Breastfeeding: The safety of Cyclizine during breastfeeding is not well established. Consult your clinical pharmacist or healthcare provider for advice tailored to your situation.


Side Effects and Precautions


Some common Cyclizine side effects include drowsiness, dry mouth, and blurred vision. These are generally mild and tend to resolve on their own.

To manage these side effects, stay hydrated, avoid driving or operating heavy machinery if you feel drowsy, and consult your pharmacist for additional advice on mitigating these effects.


When to seek medical attention?


Though rare, Cyclizine can cause serious side effects such as severe allergic reactions, confusion, and difficulty urinating.

If you experience symptoms like swelling of the face, lips, or throat, intense dizziness, or trouble breathing, seek immediate medical attention.


Conclusion


Cyclizine is a versatile and effective medication for managing nausea, vomiting, and motion sickness. You can make informed decisions about its use by understanding its uses, dosage, and potential side effects. Always consult your healthcare provider or pharmacist for personalized advice and comprehensive pharmacy services.


FAQs


What is the drug Cyclizine used for?

Cyclizine primarily prevents and treats nausea, vomiting, and dizziness caused by motion sickness. It is also effective for managing postoperative nausea and vomiting and can be used during pregnancy to alleviate morning sickness under the guidance of a healthcare provider.

Is Cyclizine anticholinergic?

When should you not use Cyclizine?

Is Cyclizine sedating?



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